A 2008 clinical review assessed how well CBD works to relieve chronic pain. The review looked at studies conducted between the late 1980s and 2007.
Based on these reviews, medical professionals concluded that CBD was effective in overall pain management without adverse side effects. They also noted that CBD was beneficial in treating insomnia related to chronic pain.
The authors of the study also note that CBD oil was most helpful in people with multiple sclerosis (MS).
Kills or Slows Bacterial Growth
CBD have the most potential for consumer use because they are non-psychotropic. Besides identifying antibacterial capability, the researchers wanted to figure out why these cannabinoids are so good at killing bacteria.
They obviously are very effective at specifically targeting some vital process in the bacteria. Unfortunately, even after extensive work at modifying the cannabinoids and comparing their activities, that targeting mechanism remains a mystery. The scientists were able to figure out that the position of the n-pentyl chain relative to the terpenoid moiety serves to control lipid affinity.
Reduces Blood Sugar Levels
In 2013, the results of a five-year study into the effects of cannabis on fasting insulin and insulin resistance were published in the American Journal of Medicine. Of the 4,657 respondents, 2,554 had used cannabis in their lifetime (579 were current users and 1,975 were past users) and 2,103 had never used the drug.
The researchers found that current users of cannabis had 16% lower fasting insulin levels than respondents who had never used cannabis, as well as having 17% lower levels of insulin resistance and higher levels of HDL-C. Respondents who had used cannabis in their lifetime but were not current users showed similar but less pronounced associations, indicating that the protective effect of cannabis fades with time.
Reduces Vomiting and Nausea
Although annoying, and sometimes detrimental, the biological causes of nausea and vomiting play an important role in the progression of many species. Classified as a defensive action, the sole purpose of this response is to inhibit the digestion of toxic compounds. Since the discovery of the human endocannabinoid system (ECS), researchers have found this complex network of cannabinoid receptor sites plays a direct role in regulating both nausea and vomiting.
Reduces Seizures and Convulsions
For the study, 120 children and adolescents with Dravet Syndrome between the ages of 2 and 18 years were randomized across 23 sites in the United States and Europe to receive either CBD 20 mg/kg or placebo added to their existing treatment over a 14-week period. Seizure frequency was tracked for one month prior to the study for baseline readings, and during the course of the study.
Cannabidiol has been shown to be effective in protecting endothelial function and integrity in human coronary artery endothelial cells (HCAECs). The study demonstrated that CBD reversed the harmful effects of high glucose on HCAECs by inhibiting:
Reactive oxygen species production by mitochondria
Transendothelial migration of monocytes
Monocyte–endothelial adhesion in HCAEC
Reduces Risk of Artery Blockage
In both animal and human studies, cannabinoids have been found to cause blood vessels to vasodilate, improving blood flow and reducing blood pressure. Another study found that marijuana use before a heart attack may improve survival rate while in the hospital. CBD specifically has shown to be a vasodilator, allowing for greater blood flow and reducing the damage to arterial walls and lowers the risk of heart attack and stroke. This vasodilator effect has been shown to help normalize blood pressure.
Inhibits Cell Growth in Tumors/Cancer Cells
What the researchers discovered was that both isolated CBD and the cannabis extracts, even at varying concentrations, were effective at inhibiting the proliferation of cervical cancer cells.
However, further examination revealed that it was the presence of CBD that was responsible for inducing apoptosis, a process that kills the cancerous cells. In addition, even at lower concentrations, isolated CBD was found to be more effective at inducing apoptosis than when it’s still blended with the other compounds that make up cannabis extracts.
Tranquilizes and is Used to Manage Psychosis
In the light of the information mentioned above, it can be taken for granted that although CBD oil treatment for mental conditions is only in its infancy, the substantial evidence which is being gained with the help of medical researches and studies depicts that it is going to be a promising drug for the treatment of Schizophrenia and psychosis in the near future.
Not only does the CBD oil turn out to be highly effective against such conditions, but it does happen to be quite safe and well-tolerated by the body.
Suppresses Muscles Spasms
As evident from the information mentioned above, it can almost be taken for granted that there are multiple different medicinal benefits of CBD which are likely to be utilized in various drugs in the years to come.
Thanks to its muscle and vascular relaxant properties, it is highly effective in the patients with inflammatory diseases with pain as a significant feature of it.
Brazilian researchers conducted a small double-blind study of patients afflicted with generalized social anxiety. After consuming CBD, participants reported a significant decrease in anxiety. Researchers validated patients’ subjective reports by performing brain scans showing cerebral blood flow patterns consistent with an anti-anxiety effect.
Promotes Bone Growth
Cannabinoid ligands regulate bone mass, but skeletal effects of cannabis (marijuana and hashish) have not been reported. Bone fractures are highly prevalent, involving prolonged immobilization and discomfort. Here we report that the major non-psychoactive cannabis constituent, cannabidiol (CBD), enhances the biomechanical properties of healing rat mid-femoral fractures.
Helps the Immune System
If there is an imbalance between cell-mediated and humoral immunity, it results in disease and dysfunction. For example, multiple sclerosis is an example of an autoimmune disease, in which the cell-mediated immune system is hyper-activated against the individual’s own brain and nervous system—as if it were foreign. Interestingly, the ECS and cannabinoids have been shown to play a key role in “balancing” the various arms and components of the immune system.
Protects Against Nervous System Degeneration
The human body has a fatty acid called amide hydroxylase (FAAH), an enzyme which and breaks down the neurotransmitter, anandamide, which is associated with the neural generation of motivation and pleasure, as well as neural development in early stage embryos.
CBD suppresses the effect of FAAH in the body, creating higher levels of anandamide, which in turn naturally binds to Cannabinoid type 1 receptors (known as CB1), which are concentrated in our central nervous systems.
Clinical trials have shown us that CBD is effective against conditions such as seizures, inflammation, nausea, stiff muscles, mild to severe anxiety, and psychosis.
WHAT IS CANNABIDIOL (CBD) OIL? WHAT DOES CBD OIL DO?
So what is CBD oil? Derived from the stalk and seed of cannabis (hemp) plants, cannabidiol (CBD) oil or CBD hemp oil is a natural botanical concentrate that is high in the compound CBD. Of the more than 85 cannabinoids so far identified in the cannabis plant, CBD is the second most common after tetrahydrocannabinol (THC). Unlike THC, CBD is non-psychotropic and therefore doesn’t cause a euphoric high.
CBD hemp oil is extracted from the cannabis varieties that are naturally abundant in CBD, and low in THC. A specialized extraction process is used to yield highly concentrated CBD oil that also contains other nutritious material such as omega-3 fatty acids, terpenes, vitamins, chlorophyll, amino acids, and other phytocannabinoids like cannabichromene (CBD), cannabigerol (CBG), cannabinol (CBN) and cannabidivarin (CBCV).
Pure hemp cannabidiol oil can be consumed directly as a nutritional supplement. Over the years, great advances in CBD hemp oil product development have led to what are now dozens of different types of CBD hemp oil products, including capsules, drops, and even chewing gum. Concentrated CBD Hemp oil can also be infused into skin and body care products and used topically.
Our understanding of CBD cannabis oil has expanded and we’re more aware today than ever of the cannabinoid’s potential. Studies on CBD’s natural health benefits are extensive and groundbreaking research is being done regularly.